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Authors: Aigbokhaode AQ, Orhue NL, Ofili AN, Oseji M, Osiatuma VA, Ezunu EO, Caleb D, Peter-Enyi L
Authors: Obu Sylvia Ifeoma, Asiodu Anthony Uchenna, Osiatuma Victor Azubuike, Ojimba Anastacia Okwudili, Oburo Ngozichukwuka Andrew, Iyasele Anthony Chukwuemeka, Nnanna Tochi Praise, Aigbokhaode Adesuwa, Dibigbo-Ibeaji Ndudi, Jisieike Obianuju Nkemjika,
Edet Samuel Eno, Sadoh Odion Rosemary
Authors: Sylvia Ifeoma Obu, Anthony Uchenna Asiodu, Victor Azubuike Osiatuma, Anastacia Okwudili Ojimba, Ngozichukwuka Andrew Oburo, Anthony Chukwuemeka Iyasele, Efe Erhinyaye Omoyibo, Chinyelu Ifeoma Emekekwue, Tochi Praise Nnanna, Justina Ifeoma Chukwumah, Samuel Uchenna Eluaka, Samuel Eno Edet, Queen Adesuwa Aigbokhaede, Ndudi Dibigbo-Ibeaji, Obianuju Nkemjika Jisieike, Ugoeze Francis Chinedu, Rosemary Odion Sadoh, Destiny Osarumwense Imade
Authors: Ngozi Esther Ezunu, Joy Ifeyinwa Egeonu, Ajiri Henry Osihro, Uyi-Oghosa Onyemushani, Said Abdulkareem, Omole Clementina Oyakhire, Onyema Edith Wayemeru, Chidera Olivia Okey-Ezufo, Chikadibia Eze-Otulaka, Faith Inegbejie, Clever Ajiri Oghale, Diana Chinenye Ofomata, Grace Nnenna Onubogu, Orhomuromo Paul Okpomo,
Eguolo Unique Okorhi, Onobhase Theresa Agbele, Anastacia Okwudili Ojimba, Adesuwa Queen Aigbokhaode, Francis Chinedu Ugoeze, Victor Azubike Osiatuma, Emmanuel Okechukwu Ezunu, Obianuju Nkemjika Jisieike, Erhinyaye Omoyibo Efe
Authors: Chukwudi Christian Umenzekwe, Anastacia Okwudili Ojimba, Francis Chinedu Ugoeze, Uchechukwu Mkpuma, Tochukwu Praise Nnanna, Juliet Ijeoma Mmerem, Chibuzor Ifeanyi Okpala, Jude Ikedinachi Okereke, Ogochukwu Ifeanyi Ezejiofor, Henry Madu Nwankwo, Omokhowa Tito Asekhame, Angus Ejidike Onyido, Uchenna Victor Nwadi
Authors: Jisieike O.N, Ojimba A.O, Omoyibo E.E., Egli P.O, Obu S.I., Ugoeze F.C, Ihudiebube-Splendor C.N, Jisieike-Onuigbo N.N, Jisieike C.F, Ilikannu S.O, Ude D.N.
ABSTRACT
Background:
Urinary tract infections (UTIs) are a significant public health concern, with bacteria responsible for 95% of cases.
Objective:
Identify main bacteria isolates and antibiotic susceptibility patterns in UTIs at Federal Medical Centre, Asaba.
Methodology:
Retrospective cross sectional study (2019-2022) reviewing laboratory records.
Results:
1. 2113 samples analyzed (683 males,1430 females),
2. Predominant bacteria: Escherichia coli (41.9%) , Staphylococcus aureus(42.9%), klebsiella spp (11%).
3. Female subjects had higher isolation rates (66.7%) than males (33.3%).
4. High resistance rates observed against tested antibiotics.
Conclusion:
Gram-negative bacteria, particularly E.coli, were the main cause of UTIs, with most isolates showing multidrug resistance and extended-spectrum beta-lactamase production.
Authors:
Sylvia Ifeoma Obu, Anthony Uchenna Asiodu, Victor Azubuike Osiatuma, Anastacia Okwudili Ojimba, Ngozichukwuka Andrew Oburo, Anthony Chukwuemeka Iyasele, Efe Erhinyaye Omoyibo, Chinyelu Ifeoma Emekekwue, Tochi Praise Nnanna, Justina Ifeoma Chukwumah, Samuel Uchenna Eluaka, Samuel Eno Edet, Queen Adesuwa Aigbokhaede, Ndudi Dibigbo-Ibeaji, Obianuju Nkemjika Jisieike, Ugoeze Francis Chinedu, Rosemary Odion Sadoh, Destiny Osarumwense Imade
ABSTRACT
The study evaluated antibiotic prescription patterns and treatment outcomes among hospitalized Covid 19 patients at the Centre for Disease Control an Research, Federal Medical Centre, Asaba, Delta State, Nigeria during the first and second wave of the pandemic. A retrospective review of 122 patient records examined demographic data, antibiotic use, dose regimen, hospitalizations length and commodities. The study aimed to determine antibiotic prescription patterns and treatment outcomes (primary outcomes) and identify factors predicting patient recovery (Secondary outcomes). Chi square analysis and Fisher's test were utilized to obtain the primary outcomes and the secondary outcome was derived using regression analysis. A total of 299 antibiotics from 10 classes were prescribed with 98.4% of patients receiving azithromicin and penicillin/macrolides Among the patients, 40 completed treatments at home. 53 had commodities, 19 died, 100 recovered. Poor treatment outcomes were linked to older age, commodities and multiple antibiotic combinations, while gender, hospitalizations length and Antibiotic type did not significantly impact recovery. No significant differences were found in antibiotic prescriptions between patients with and without bacterial co-infections. These findings highlight the role of compromised immunity in poor outcomes and underscore the importance of evidence based antibiotic use during outbreaks to enhance patient management and curb antimicrobial resistance.
Authors:
Ibukun Akinkunmi, Ayodapo Oluwa dare Jegede, Stella Chinyere Onyegazi, Benjamin Agbamudia, Sylvia Ifeoma Obu, Victor Azubuike Osiatuma, Anastacia Okwudili Ojimba, Efe Erhinyaye Omoyibo, Queen Adesuwa Aigbokhaede, Ugoeze Francis Chinedu, Kate Ugochi Akinkunmi, Obianuju Jisieike
ABSTRACT
The retrospective study, determined the antimicrobial sensitivity Isolates from stool samples at the Federal Medical Centre, Asaba, Nigeria (2019-2022). Escherichia coli and salmonella were the most frequently identified pathogens, with high resistance to fluoroquinolones and gentamycin. The study highlights for improved sanitation, vaccination, antibiotic stewardship, and alternate therapies to address the public health concern of antibiotic resistance.
Authors:
Ibukun Akinkunmi, Eborah C. C., Apeh Ekedegwa Daniel, Benjamin Agbamudia, Sylvia Ifeoma Obu, Eduvie T. A., Emekekwue C. I., Queen Adesuwa Aigbokhaede, Ugoeze Francis Chinedu, Edet S. E., Edom A. C., Afamefune J. U., Nnanna P. T., Dibigbo Ibiaji N., Agbamudia B., Ugochi Akinkunmi.
ABSTRACT
Background : Mother to Child Transmission (MTCT) of HIV continues to be a critical public health issue, particularly in high-Prevalence regions. This study examines the rates of MTCT in relation to antenatal booking, parity, antiretroviral (ARV) use, delivery mode, CD4 counts, and infant feeding practices.
Methods: A retrospective cross sectional study was conducted at the Federal Medical Centre, Asaba, Nigeria, involving pregnant women living with HIV attending the prevention of mother to Child Transmission (PMTCT) Program. Data on demographics, antenatal booking. ARV use, delivery mode, CD4 count, and infant feeding were collected. Ethical approval was obtained from the hospital's ethics committee. MTCT rates were analysed based on these variables.
Results: MTCT rates dropped from 1.2% in 2018 to 0% in 2019, with ARV use showed lower MTCT rates were associated with CD4 counts below 200 cells/mm^3, emphasizing the importance of early Art initiation. Exclusive breastfeeding with ARV prophylaxis was the most effective practice.
Conclusion: The PMTCT program at FMC Asaba significantly reduced MTCT rates, highlighting the importance of early booking, ARV adherence, and appropriate delivery methods in improving maternal-child health in high HIV Prevalence areas.
Authors:
Ibukun Jacob Akinkunmi, Ayodapo Oluwa dare Jegede, Ekedegwa Daniel Apeh, Uzuazuraro Michael Otuaga, Francis Ugoeze, Adesuwa Queen Aigbokhaode, Sylvia Ifeoma Obu, Evangeline Natalie Enaike, Efe Omoyibo, Victor Osiatuma, Samuel Okwuchukwu Ilikannu, Emwinlogosa Kenneth Guobadia, Benjamin Agbamudia, Johnson Eleojo Odaudu and Kate Akinkunmi